當(dāng)前位置:首頁 > 產(chǎn)品中心 > 抗體/抗原 > 標(biāo)記一抗 > bs-4906R-BioBiotin標(biāo)記的細(xì)胞膜鐵轉(zhuǎn)運(yùn)蛋白FP1抗體
簡要描述:SLC40A1 may be involved in iron export from duodenal epithelial cells and also in transfer of iron between maternal and fetal circulation. It mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin). Defects in SLC40A1 are the cause of hemochromatosis type 4, an autosomal dominant iron-loading disorder characterized by early iron accumulation in reticuloendothelial cells and a marked increase in serum ferritin.
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