當前位置:首頁 > 產(chǎn)品中心 > 抗體/抗原 > 標記一抗 > bs-12418R-PEPE標記的腫瘤轉(zhuǎn)移抑制蛋白BAMBI抗體
簡要描述:BAMBI is a membrane spanning glycoprotein that acts as a negative regulator of TGF-β signaling during development. The BAMBI family of proteins are related to type I TGF-β receptor family, however, BAMBI is a pseudoreceptor that lacks an intracellular serine/threonine kinase domain. BAMBI transcription regulation is under the influence of β-catenin, BMP, smad3 and smad4. BAMBI expression can increase in colorectal and hepatocellular carcinomas relative to non-cancerous tissues. BAMBI is ex
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